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HPLC-based activity profiling for GABA(A) receptor modulators from the traditional Chinese herbal drug Kushen (Sophora flavescens root)
An EtOAc extract from the roots of Sophora flavescens (Kushen) potentiated γ -aminobutyric acid (GABA)-induced chloride influx in Xenopus oocytes transiently expressing GABA(A) receptors with subunit composition, α(1)β(2)γ(2S). HPLC-based activity profiling of the extract led to the identification o...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3196987/ https://ncbi.nlm.nih.gov/pubmed/21207144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11030-010-9297-7 |
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