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Targeting HSP90 in ovarian cancers with multiple receptor tyrosine kinase coactivation
BACKGROUND: Ovarian cancer has the highest mortality rate of all gynecologic malignancy. The receptor tyrosine kinases (RTKs), including EGFR, ERBB2, PDGFR, VEGFR and MET, are activated in subsets of ovarian cancer, suggesting that these kinases might represent novel therapeutic targets. However, cl...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3196924/ https://ncbi.nlm.nih.gov/pubmed/21962244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-10-125 |
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