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Histidine modification with diethyl pyrocarbonate shows heterogeneity of benzodiazepine receptors.

The effect of diethyl pyrocarbonate modification of histidine on the specific binding of [3H]diazepam and its enhancement with muscimol and (+/-)-pentobarbital was investigated. Diethyl pyrocarbonate treatment produced a dose-related inhibition of specific [3H]diazepam binding to rat brain membranes...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Burch, T P, Ticku, M K
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1981
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC319690/
https://ncbi.nlm.nih.gov/pubmed/6267611
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