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Histidine modification with diethyl pyrocarbonate shows heterogeneity of benzodiazepine receptors.

The effect of diethyl pyrocarbonate modification of histidine on the specific binding of [3H]diazepam and its enhancement with muscimol and (+/-)-pentobarbital was investigated. Diethyl pyrocarbonate treatment produced a dose-related inhibition of specific [3H]diazepam binding to rat brain membranes...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Burch, T P, Ticku, M K
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1981
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319690/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6267611/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.6.3945
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