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Diethyl pyrocarbonate modification of the ryanodine receptor/Ca2+ channel from skeletal muscle.

Exposure of junctional sarcoplasmic reticulum (SR) membranes or purified ryanodine receptor to the histidine-specific reagent diethyl pyrocarbonate (DEPC) led to concentration- and time-dependent inactivation of ryanodine binding. The pH-dependence of the inactivation of ryanodine binding by DEPC an...

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Main Authors: Shoshan-Barmatz, V, Weil, S
格式: Artigo
語言:Inglês
出版: 1994
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1138038/
https://ncbi.nlm.nih.gov/pubmed/8166637
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