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Genomic imprinting at a boundary element flanking the SDHD locus

Germline mutations in SDHD, a mitochondrial complex II (succinate dehydrogenase) subunit gene at chromosome band 11q23, cause highly penetrant paraganglioma (PGL) tumors when transmitted through fathers. In contrast, maternal transmission rarely, if ever, leads to tumor development. The mechanism un...

詳細記述

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書誌詳細
主要な著者: Baysal, Bora E., McKay, Sharen E., Kim, Yoon Jung, Zhang, Zimei, Alila, Linda, Willett-Brozick, Joan E., Pacak, Karel, Kim, Tae Hoon, Shadel, Gerald S.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196894/
https://ncbi.nlm.nih.gov/pubmed/21862453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr376
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