Benzodiazepines have high-affinity binding sites and induce melanogenesis in B16/C3 melanoma cells.
We found that two markers of differentiation, tyrosinase (monophenol, dihydroxyphenylalanine:oxygen oxidoreductase, EC 1.14.18.1) activity and melanin synthesis, are induced by diazepam in B16/C3 mouse melanoma cells. We also demonstrated high-affinity binding sites for [3H]diazepam in these cells b...
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| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1981
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319688/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6267610/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.6.3935 |
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