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A Rab11a-enriched subapical membrane compartment regulates a cytoskeleton-dependent transcytotic pathway in secretory epithelial cells of the lacrimal gland

Despite observations that the lacrimal gland has been identified as the principal source of dimeric immunoglobulin A (dIgA) in tears, the mechanism used by lacrimal gland acinar cells (LGACs) to transcytose dIgA produced by interstitial plasma cells is not well-characterized. This study identifies a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Xu, Shi, Edman, Maria, Kothawala, Mubashera S., Sun, Guoyong, Chiang, Lilian, Mircheff, Austin, Zhu, Lixin, Okamoto, Curtis, Hamm-Alvarez, Sarah
Format: Artigo
Sprache:Inglês
Veröffentlicht: Company of Biologists 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196860/
https://ncbi.nlm.nih.gov/pubmed/21984810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.088906
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