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A Comprehensive Approach to the Profiling of the Cooked Meat Carcinogens 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline, 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and their Metabolites in Human Urine

A targeted liquid chromatography/tandem mass spectrometry-based metabolomics-type approach, employing a triple stage quadrupole mass spectrometer in the product ion scan and selected reaction monitoring modes, was established to profile 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx), 2-amino-...

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Detalhes bibliográficos
Main Authors: Gu, Dan, McNaughton, Lynn, LeMaster, David, Lake, Brian G., Gooderham, Nigel J., Kadlubar, Fred F., Turesky, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196554/
https://ncbi.nlm.nih.gov/pubmed/20192249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx900436m
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