Oncolytic Adenoviruses Armed with Thymidine Kinase Can Be Traced by PET Imaging and Show Potent Antitumoural Effects by Ganciclovir Dosing

Replication-competent adenoviruses armed with thymidine kinase (TK) combine the concepts of virotherapy and suicide gene therapy. Moreover TK-activity can be detected by noninvasive positron emission-computed tomography (PET) imaging, what could potentially facilitate virus monitoring in vivo. Here,...

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Detalhes bibliográficos
Main Authors: Abate-Daga, Daniel, Andreu, Nuria, Camacho-Sánchez, Juan, Alemany, Ramon, Herance, Raúl, Millán, Olga, Fillat, Cristina
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196510/
https://ncbi.nlm.nih.gov/pubmed/22028820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026142
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