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The Alpha Subunit of Eukaryotic Initiation Factor 2B (eIF2B) Is Required for eIF2-Mediated Translational Suppression of Vesicular Stomatitis Virus
Eukaryotic translation initiation factor 2B (eIF2B) is a heteropentameric guanine nucleotide exchange factor that converts protein synthesis initiation factor 2 (eIF2) from a GDP-bound form to the active eIF2-GTP complex. Cellular stress can repress translation initiation by activating kinases capab...
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Main Authors: | , , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
American Society for Microbiology
2011
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3196436/ https://ncbi.nlm.nih.gov/pubmed/21795329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05146-11 |
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