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Electrospray MS/MS reveals extensive and nonspecific oxidation of cholesterol esters in human peripheral vascular lesions

Although LDL is rendered proatherogenic by various experimental treatments (e.g., acetylation), the exact structural changes that drive LDL transformation in vivo remain enigmatic. Among the many hypothesized targets of oxidative modification are cholesterol esters (CE). This family of neutral lipid...

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Detalhes bibliográficos
Main Authors: Hutchins, Patrick M., Moore, Ernest E., Murphy, Robert C.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196238/
https://ncbi.nlm.nih.gov/pubmed/21885431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M019174
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