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Focussed Ion Beam Milling and Scanning Electron Microscopy of Brain Tissue

This protocol describes how biological samples, like brain tissue, can be imaged in three dimensions using the focussed ion beam/scanning electron microscope (FIB/SEM). The samples are fixed with aldehydes, heavy metal stained using osmium tetroxide and uranyl acetate. They are then dehydrated with...

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Detalhes bibliográficos
Main Authors: Knott, Graham, Rosset, Stéphanie, Cantoni, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196160/
https://ncbi.nlm.nih.gov/pubmed/21775953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/2588
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