Adaptor Protein-3 (AP-3) Complex Mediates the Biogenesis of Acidocalcisomes and Is Essential for Growth and Virulence of Trypanosoma brucei

Acidocalcisomes are acidic calcium and polyphosphate storage organelles found in a diverse range of organisms. Here we present evidence that the biogenesis of acidocalcisomes in Trypanosoma brucei is linked to the expression of adaptor protein-3 (AP-3) complex. Localization studies in cell lines exp...

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Bibliographische Detailangaben
Hauptverfasser: Huang, Guozhong, Fang, Jianmin, Sant'Anna, Celso, Li, Zhu-Hong, Wellems, Dianne L., Rohloff, Peter, Docampo, Roberto
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Microbiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196089/
https://ncbi.nlm.nih.gov/pubmed/21880705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.284661
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