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The acidocalcisome inositol-1,4,5-trisphosphate receptor of Trypanosoma brucei is stimulated by luminal polyphosphate hydrolysis products

Acidocalcisomes are acidic calcium stores rich in polyphosphate (polyP) and are present in trypanosomes and also in a diverse range of other organisms. Ca(2+) is released from these organelles through a channel, inositol 1,4,5-trisphosphate receptor (TbIP(3)R), which is essential for growth and infe...

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Potapenko, Evgeniy, Negrão, Núria W., Huang, Guozhong, Docampo, Roberto
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6615701/
https://ncbi.nlm.nih.gov/pubmed/31138655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007906
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