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Acidocalcisomes of Trypanosoma brucei have an inositol 1,4,5-trisphosphate receptor that is required for growth and infectivity

Acidocalcisomes are acidic calcium stores rich in polyphosphate and found in a diverse range of organisms. The mechanism of Ca(2+) release from these organelles was unknown. Here we present evidence that Trypanosoma brucei acidocalcisomes possess an inositol 1,4,5-trisphosphate receptor (TbIP(3)R) f...

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Detalhes bibliográficos
Main Authors: Huang, Guozhong, Bartlett, Paula J., Thomas, Andrew P., Moreno, Silvia N. J., Docampo, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3562765/
https://ncbi.nlm.nih.gov/pubmed/23319604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216955110
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