Chitosan but Not Chitin Activates the Inflammasome by a Mechanism Dependent upon Phagocytosis

Chitin is an abundant polysaccharide found in fungal cell walls, crustacean shells, and insect exoskeletons. The immunological properties of both chitin and its deacetylated derivative chitosan are of relevance because of frequent natural exposure and their use in medical applications. Depending on...

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Autors principals: Bueter, Chelsea L., Lee, Chrono K., Rathinam, Vijay A. K., Healy, Gloria J., Taron, Christopher H., Specht, Charles A., Levitz, Stuart M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195641/
https://ncbi.nlm.nih.gov/pubmed/21862582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.274936
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