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Spectrum and Mechanisms of Inflammasome Activation by Chitosan

Chitosan, the deacetylated derivative of chitin, can be found in the cell wall of some fungi and is utilized in translational applications. We have shown that highly purified preparations of chitosan, but not chitin, activate the NLRP3 inflammasome in primed mouse bone marrow-derived macrophages (BM...

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Detalhes bibliográficos
Main Authors: Bueter, Chelsea L., Lee, Chrono K., Wang, Jennifer P., Ostroff, Gary R., Specht, Charles A., Levitz, Stuart M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063524/
https://ncbi.nlm.nih.gov/pubmed/24829412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301695
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