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GTP-dependent Binding and Nuclear Transport of RNA Polymerase II by Npa3 Protein

We identified XAB1 in a proteomic screen for factors that interact with human RNA polymerase II (RNAPII). Because XAB1 has a conserved Saccharomyces cerevisiae homologue called Npa3, yeast genetics and biochemical analysis were used to dissect the significance of the interaction. Degron-dependent Np...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Staresincic, Lidija, Walker, Jane, Dirac-Svejstrup, A. Barbara, Mitter, Richard, Svejstrup, Jesper Q.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195585/
https://ncbi.nlm.nih.gov/pubmed/21844196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.286161
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