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TRAF6 is an amplified oncogene bridging the RAS and NF-κB pathways in human lung cancer

Somatic mutations and copy number alterations (as a result of deletion or amplification of large portions of a chromosome) are major drivers of human lung cancers. Detailed analysis of lung cancer–associated chromosomal amplifications could identify novel oncogenes. By performing an integrative cyto...

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Detalhes bibliográficos
Main Authors: Starczynowski, Daniel T., Lockwood, William W., Deléhouzée, Sophie, Chari, Raj, Wegrzyn, Joanna, Fuller, Megan, Tsao, Ming-Sound, Lam, Stephen, Gazdar, Adi F., Lam, Wan L., Karsan, Aly
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195480/
https://ncbi.nlm.nih.gov/pubmed/21911935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI58818
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