Mutagen-induced resistance to mycophenolic acid in hamster cells can be associated with increased inosine 5'-phosphate dehydrogenase activity.

Cell variants resistant to the cytotoxic effect of mycophenolic acid, an inhibitor of IMP dehydrogenase (IMP:NAD+ oxidoreductase, EC 1.2.1.14), were selected by a one-step procedure from Chinese hamster V79 cells. The frequency of these variants was increased in a dose-dependent manner after treatme...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Huberman, E, McKeown, C K, Friedman, J
Médium: Artigo
Jazyk:Inglês
Vydáno: 1981
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC319518/
https://ncbi.nlm.nih.gov/pubmed/6114490
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky