Detailed kinetics and regulation of mammalian 2-oxoglutarate dehydrogenase

BACKGROUND: Mitochondrial 2-oxoglutarate (α-ketoglutarate) dehydrogenase complex (OGDHC), a key regulatory point of tricarboxylic acid (TCA) cycle, plays vital roles in multiple pathways of energy metabolism and biosynthesis. The catalytic mechanism and allosteric regulation of this large enzyme com...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Qi, Feng, Pradhan, Ranjan K, Dash, Ranjan K, Beard, Daniel A
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2011
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195097/
https://ncbi.nlm.nih.gov/pubmed/21943256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-12-53
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