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Detailed kinetics and regulation of mammalian 2-oxoglutarate dehydrogenase
BACKGROUND: Mitochondrial 2-oxoglutarate (α-ketoglutarate) dehydrogenase complex (OGDHC), a key regulatory point of tricarboxylic acid (TCA) cycle, plays vital roles in multiple pathways of energy metabolism and biosynthesis. The catalytic mechanism and allosteric regulation of this large enzyme com...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BioMed Central
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3195097/ https://ncbi.nlm.nih.gov/pubmed/21943256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-12-53 |
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