Distal Leucines Are Key Functional Determinants of Alix-Binding Simian Immunodeficiency Virus SIV(smE543) and SIV(mac239) Type 3 L Domains

In addition to PTAP L domains, primate lentiviruses carry Alix-binding motifs that include the recently described type 3 SREKPYKEVTEDLLHLNSLF sequence. We examined the requirements for the type 3 sequence motif in simian immunodeficiency virus SIV(smE543) and identified the (499)LNSLF(503) sequence...

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Autores principales: Bello, Nana F., Wu, Fan, Sette, Paola, Dussupt, Vincent, Hirsch, Vanessa M., Bouamr, Fadila
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2011
Materias:
Structure and Assembly
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3194945/
https://ncbi.nlm.nih.gov/pubmed/21849430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05284-11
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