Cargando...

Identification of the HIV-1 NC Binding Interface in Alix Bro1 Reveals a Role for RNA

HIV-1 recruits members of ESCRT, the cell membrane fission machinery that promotes virus exit. HIV-1 Gag protein gains access to ESCRT directly by binding Alix, an ESCRT-associated protein that promotes budding. The Alix Bro1 and V domains bind Gag NC and p6 regions, respectively. Whereas V-p6 bindi...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Sette, Paola, Dussupt, Vincent, Bouamr, Fadila
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2012
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486338/
https://ncbi.nlm.nih.gov/pubmed/22896625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01260-12
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!