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A Human TREK-1/HEK Cell Line: A Highly Efficient Screening Tool for Drug Development in Neurological Diseases

TREK-1 potassium channels are involved in a number of physiopathological processes such as neuroprotection, pain and depression. Molecules able to open or to block these channels can be clinically important. Having a cell model for screening such molecules is of particular interest. Here, we describ...

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Hlavní autoři: Moha ou Maati, Hamid, Peyronnet, Rémi, Devader, Christelle, Veyssiere, Julie, Labbal, Fabien, Gandin, Carine, Mazella, Jean, Heurteaux, Catherine, Borsotto, Marc
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3194802/
https://ncbi.nlm.nih.gov/pubmed/22022421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025602
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