Altered Trek-1 Function in Sortilin Deficient Mice Results in Decreased Depressive-Like Behavior

The background potassium channel TREK-1 has been shown to be a potent target for depression treatment. Indeed, deletion of this channel in mice resulted in a depression resistant phenotype. The association of TREK-1 with the sorting protein sortilin prompted us to investigate the behavior of mice de...

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Dades bibliogràfiques
Publicat a:Front Pharmacol
Autors principals: Moreno, Sébastien, Devader, Christelle M., Pietri, Mariel, Borsotto, Marc, Heurteaux, Catherine, Mazella, Jean
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6088259/
https://ncbi.nlm.nih.gov/pubmed/30127743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00863
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