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Altered Trek-1 Function in Sortilin Deficient Mice Results in Decreased Depressive-Like Behavior
The background potassium channel TREK-1 has been shown to be a potent target for depression treatment. Indeed, deletion of this channel in mice resulted in a depression resistant phenotype. The association of TREK-1 with the sorting protein sortilin prompted us to investigate the behavior of mice de...
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| Udgivet i: | Front Pharmacol |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6088259/ https://ncbi.nlm.nih.gov/pubmed/30127743 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00863 |
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