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Microtubule-binding agents: a dynamic field of cancer therapeutics

Microtubules are dynamic filamentous cytoskeletal proteins that are an important therapeutic target in tumor cells. Microtubule binding agents have been part of the pharmacopoeia of cancer for decades, and until the advent of targeted therapy microtubules were the only alternative to DNA as a therap...

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Detalhes bibliográficos
Main Authors: Dumontet, Charles, Jordan, Mary Ann
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3194401/
https://ncbi.nlm.nih.gov/pubmed/20885410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd3253
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