Wird geladen...

Modeling the Effects of Drug Binding on the Dynamic Instability of Microtubules

We propose a stochastic model that accounts for the growth, catastrophe and rescue processes of steady state microtubules assembled from MAP-free tubulin in the possible presence of a microtubule associated drug. As an example for the latter, we both experimentally and theoretically study the pertur...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Hinow, Peter, Rezania, Vahid, Lopus, Manu, Jordan, Mary Ann, Tuszyński, Jack A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3168699/
https://ncbi.nlm.nih.gov/pubmed/21836336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1478-3975/8/5/056004
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!