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Modeling the Effects of Drug Binding on the Dynamic Instability of Microtubules
We propose a stochastic model that accounts for the growth, catastrophe and rescue processes of steady state microtubules assembled from MAP-free tubulin in the possible presence of a microtubule associated drug. As an example for the latter, we both experimentally and theoretically study the pertur...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3168699/ https://ncbi.nlm.nih.gov/pubmed/21836336 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1478-3975/8/5/056004 |
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