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Mutations in the gene coding for Escherichia coli DNA topoisomerase I affect transcription and transposition.

Mutations in top, the structural gene for Escherichia coli DNA topoisomerase I, have been identified and mapped at 28 min on the chromosome, near cysB. Strains carrying deletions of the top gene are viable. The top mutations, however, do exert pleiotropic effects on transcription and transposition....

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Sternglanz, R, DiNardo, S, Voelkel, K A, Nishimura, Y, Hirota, Y, Becherer, K, Zumstein, L, Wang, J C
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1981
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319434/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6265907/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.5.2747
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