Mutations in the gene coding for Escherichia coli DNA topoisomerase I affect transcription and transposition.

Mutations in top, the structural gene for Escherichia coli DNA topoisomerase I, have been identified and mapped at 28 min on the chromosome, near cysB. Strains carrying deletions of the top gene are viable. The top mutations, however, do exert pleiotropic effects on transcription and transposition....

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Main Authors: Sternglanz, R, DiNardo, S, Voelkel, K A, Nishimura, Y, Hirota, Y, Becherer, K, Zumstein, L, Wang, J C
格式: Artigo
語言:Inglês
出版: 1981
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC319434/
https://ncbi.nlm.nih.gov/pubmed/6265907
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