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Characterization of pathogenic germline mutations in human Protein Kinases

BACKGROUND: Protein Kinases are a superfamily of proteins involved in crucial cellular processes such as cell cycle regulation and signal transduction. Accordingly, they play an important role in cancer biology. To contribute to the study of the relation between kinases and disease we compared patho...

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Bibliografische gegevens
Hoofdauteurs: Izarzugaza, Jose MG, Hopcroft, Lisa EM, Baresic, Anja, Orengo, Christine A, Martin, Andrew CR, Valencia, Alfonso
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3194193/
https://ncbi.nlm.nih.gov/pubmed/21992016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-S4-S1
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