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Characterization of pathogenic germline mutations in human Protein Kinases

BACKGROUND: Protein Kinases are a superfamily of proteins involved in crucial cellular processes such as cell cycle regulation and signal transduction. Accordingly, they play an important role in cancer biology. To contribute to the study of the relation between kinases and disease we compared patho...

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Main Authors: Izarzugaza, Jose MG, Hopcroft, Lisa EM, Baresic, Anja, Orengo, Christine A, Martin, Andrew CR, Valencia, Alfonso
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3194193/
https://ncbi.nlm.nih.gov/pubmed/21992016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-S4-S1
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