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Interpretation of the Consequences of Mutations in Protein Kinases: Combined Use of Bioinformatics and Text Mining

Protein kinases play a crucial role in a plethora of significant physiological functions and a number of mutations in this superfamily have been reported in the literature to disrupt protein structure and/or function. Computational and experimental research aims to discover the mechanistic connectio...

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Detalhes bibliográficos
Main Authors: Izarzugaza, Jose M. G., Krallinger, Martin, Valencia, Alfonso
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3449330/
https://ncbi.nlm.nih.gov/pubmed/23055974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2012.00323
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