Expression of the hepatitis B virus surface antigen gene in cell culture by using a simian virus 40 vector
We have constructed a simian virus 40 recombinant carrying a fragment of DNA from hepatitis B virus. Cultured monkey kidney cells infected with this recombinant produce hepatitis B surface antigen. The antigen is excreted into the culture medium as 22-nm particles with the same physical properties,...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1981
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319398/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6264484/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.4.2606 |
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