Expression of the hepatitis B virus surface antigen gene in cell culture by using a simian virus 40 vector

We have constructed a simian virus 40 recombinant carrying a fragment of DNA from hepatitis B virus. Cultured monkey kidney cells infected with this recombinant produce hepatitis B surface antigen. The antigen is excreted into the culture medium as 22-nm particles with the same physical properties,...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Moriarty, Ann M., Hoyer, Bill H., Shih, J. Wai-kuo, Gerin, John L., Hamer, Dean H.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1981
Soggetti:	Biological Sciences: Microbiology
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319398/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6264484/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.4.2606
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