Expression of the hepatitis B virus surface antigen gene in cell culture by using a simian virus 40 vector

We have constructed a simian virus 40 recombinant carrying a fragment of DNA from hepatitis B virus. Cultured monkey kidney cells infected with this recombinant produce hepatitis B surface antigen. The antigen is excreted into the culture medium as 22-nm particles with the same physical properties,...

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Bibliographic Details
Main Authors: Moriarty, Ann M., Hoyer, Bill H., Shih, J. Wai-kuo, Gerin, John L., Hamer, Dean H.
Format: Artigo
Language:Inglês
Published: 1981
Subjects:
Biological Sciences: Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC319398/
https://ncbi.nlm.nih.gov/pubmed/6264484
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