A New Structural Form in the SAM/Metal-Dependent O-methyltransferase Family: MycE from the Mycinamycin Biosynthetic Pathway

O-linked methylation of sugar substituents is a common modification in the biosynthesis of many natural products, and is catalyzed by multiple families of S-adenosyl-L-methioine (SAM or AdoMet) dependent methyltransferases. Mycinamicins, potent antibiotics from Micromonospora griseorubida, can be me...

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Detalhes bibliográficos
Main Authors: Akey, David L., Li, Shengying, Konwerski, Jamie R., Confer, Laura A., Bernard, Steffen M., Anzai, Yojiro, Kato, Fumio, Sherman, David H., Smith, Janet L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3193595/
https://ncbi.nlm.nih.gov/pubmed/21884704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.08.040
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