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Stereospecific Total Syntheses of Proteasome Inhibitors Omuralide and Lactacystin
Omuralide, a transformation product of the microbial metabolite lactacystin, was the first molecule discovered as a specific inhibitor of the proteasome and is unique in that it specifically inhibits the proteolytic activity of the 20S subunit of the proteasome without inhibiting any other protease...
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| Hoofdauteurs: | , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2011
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3193574/ https://ncbi.nlm.nih.gov/pubmed/21916437 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo201453x |
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