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Oncogene AEG-1 promotes glioma-induced neurodegeneration by increasing glutamate excitotoxicity
Aggressive tumor growth, diffuse tissue invasion and neurodegeneration are hallmarks of malignant glioma. Although glutamate excitotoxicity is considered to play a key role in glioma-induced neurodegeneration, the mechanism(s) controlling this process is poorly understood. AEG-1 is an oncogene overe...
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Autors principals: | , , , , , , , , , , , , , , |
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Format: | Artigo |
Idioma: | Inglês |
Publicat: |
2011
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3193553/ https://ncbi.nlm.nih.gov/pubmed/21852380 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-0782 |
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