Oncogene AEG-1 promotes glioma-induced neurodegeneration by increasing glutamate excitotoxicity

Aggressive tumor growth, diffuse tissue invasion and neurodegeneration are hallmarks of malignant glioma. Although glutamate excitotoxicity is considered to play a key role in glioma-induced neurodegeneration, the mechanism(s) controlling this process is poorly understood. AEG-1 is an oncogene overe...

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Main Authors: Lee, Seok-Geun, Kim, Keetae, Kegelman, Timothy P., Dash, Rupesh, Das, Swadesh K., Choi, Jung Kyoung, Emdad, Luni, Howlett, Eric L., Jeon, Hyun Yong, Su, Zhao Zhong, Yoo, Byoung Kwon, Sarkar, Devanand, Kim, Sung-Hoon, Kang, Dong-Chul, Fisher, Paul B.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3193553/
https://ncbi.nlm.nih.gov/pubmed/21852380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-0782
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