Generation of iPSCs from mouse fibroblasts with a single gene, Oct4, and small molecules

The introduction of four transcription factors Oct4, Klf4, Sox2 and c-Myc by viral transduction can induce reprogramming of somatic cells into induced pluripotent stem cells (iPSCs), but the use of iPSCs is hindered by the use of viral delivery systems. Chemical-induced reprogramming offers a novel...

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Detalhes bibliográficos
Main Authors: Li, Yanqin, Zhang, Qiang, Yin, Xiaolei, Yang, Weifeng, Du, Yuanyuan, Hou, Pingping, Ge, Jian, Liu, Chun, Zhang, Weiqi, Zhang, Xu, Wu, Yetao, Li, Honggang, Liu, Kang, Wu, Chen, Song, Zhihua, Zhao, Yang, Shi, Yan, Deng, Hongkui
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3193405/
https://ncbi.nlm.nih.gov/pubmed/20956998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2010.142
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