IL-12 selectively programs effector pathways that are stably expressed in human CD8(+) effector memory T cells in vivo

CD8(+) cytotoxic T lymphocytes play a major role in defense against intracellular pathogens, and their functions are specified by antigen recognition and innate cytokines. IL-12 and IFN-α/β are potent “signal 3” cytokines that are involved in both effector and memory cell development. Although the m...

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Hlavní autoři: Chowdhury, Fatema Z., Ramos, Hilario J., Davis, Laurie S., Forman, James, Farrar, J. David
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2011
Témata:
Immunobiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3193266/
https://ncbi.nlm.nih.gov/pubmed/21832277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-05-357111
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