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IL-12 selectively programs effector pathways that are stably expressed in human CD8(+) effector memory T cells in vivo
CD8(+) cytotoxic T lymphocytes play a major role in defense against intracellular pathogens, and their functions are specified by antigen recognition and innate cytokines. IL-12 and IFN-α/β are potent “signal 3” cytokines that are involved in both effector and memory cell development. Although the m...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society of Hematology
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3193266/ https://ncbi.nlm.nih.gov/pubmed/21832277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-05-357111 |
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