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Regulatory elements required for the activation and repression of the protocadherin-α gene cluster

The mouse protocadherin (Pcdh) -α, -β, and -γ gene clusters encode more than 50 protein isoforms, the combinatorial expression of which generates vast single-cell diversity in the brain. At present, the mechanisms by which this diversity is expressed are not understood. Here we show that two transcr...

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Autores principales: Kehayova, Polina, Monahan, Kevin, Chen, Weisheng, Maniatis, Tom
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3193253/
https://ncbi.nlm.nih.gov/pubmed/21949399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1114357108
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