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Ligand activation leads to regulated intramembrane proteolysis of fibroblast growth factor receptor 3
Fibroblast growth factor receptor 3 (FGFR3) is a major negative regulator of bone growth that inhibits the proliferation and differentiation of growth plate chondrocytes. Activating mutations of its c isoform cause dwarfism in humans; somatic mutations can drive oncogenic transformation in multiple...
Gorde:
| Egile Nagusiak: | , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
The American Society for Cell Biology
2011
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3192865/ https://ncbi.nlm.nih.gov/pubmed/21865593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-01-0080 |
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