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Down-Regulation of the Met Receptor Tyrosine Kinase by Presenilin-dependent Regulated Intramembrane Proteolysis

Hepatocyte growth factor/scatter factor (HGF/SF) acts through the membrane-anchored Met receptor tyrosine kinase to induce invasive growth. Deregulation of this signaling is associated with tumorigenesis and involves, in most cases, overexpression of the receptor. We demonstrate that Met is processe...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Foveau, Bénédicte, Ancot, Frédéric, Leroy, Catherine, Petrelli, Annalisa, Reiss, Karina, Vingtdeux, Valérie, Giordano, Silvia, Fafeur, Véronique, Tulasne, David
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The American Society for Cell Biology 2009
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2675628/
https://ncbi.nlm.nih.gov/pubmed/19297528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-09-0969
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