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Number and Size Distribution of Colorectal Adenomas under the Multistage Clonal Expansion Model of Cancer

Colorectal cancer (CRC) is believed to arise from mutant stem cells in colonic crypts that undergo a well-characterized progression involving benign adenoma, the precursor to invasive carcinoma. Although a number of (epi)genetic events have been identified as drivers of this process, little is known...

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書目詳細資料
Main Authors: Dewanji, Anup, Jeon, Jihyoun, Meza, Rafael, Luebeck, E. Georg
格式: Artigo
語言:Inglês
出版: Public Library of Science 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192823/
https://ncbi.nlm.nih.gov/pubmed/22022253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002213
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