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Number and Size Distribution of Colorectal Adenomas under the Multistage Clonal Expansion Model of Cancer

Colorectal cancer (CRC) is believed to arise from mutant stem cells in colonic crypts that undergo a well-characterized progression involving benign adenoma, the precursor to invasive carcinoma. Although a number of (epi)genetic events have been identified as drivers of this process, little is known...

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Hlavní autoři: Dewanji, Anup, Jeon, Jihyoun, Meza, Rafael, Luebeck, E. Georg
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192823/
https://ncbi.nlm.nih.gov/pubmed/22022253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002213
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