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Number and Size Distribution of Colorectal Adenomas under the Multistage Clonal Expansion Model of Cancer

Colorectal cancer (CRC) is believed to arise from mutant stem cells in colonic crypts that undergo a well-characterized progression involving benign adenoma, the precursor to invasive carcinoma. Although a number of (epi)genetic events have been identified as drivers of this process, little is known...

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Bibliografiske detaljer
Main Authors: Dewanji, Anup, Jeon, Jihyoun, Meza, Rafael, Luebeck, E. Georg
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192823/
https://ncbi.nlm.nih.gov/pubmed/22022253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002213
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