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Bacteria Modulate the CD8+ T Cell Epitope Repertoire of Host Cytosol-Exposed Proteins to Manipulate the Host Immune Response

The main adaptive immune response to bacteria is mediated by B cells and CD4+ T-cells. However, some bacterial proteins reach the cytosol of host cells and are exposed to the host CD8+ T-cells response. Both gram-negative and gram-positive bacteria can translocate proteins to the cytosol through typ...

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Detalhes bibliográficos
Main Authors: Maman, Yaakov, Nir-Paz, Ran, Louzoun, Yoram
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192822/
https://ncbi.nlm.nih.gov/pubmed/22022257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002220
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