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Modelling Reveals Kinetic Advantages of Co-Transcriptional Splicing

Messenger RNA splicing is an essential and complex process for the removal of intron sequences. Whereas the composition of the splicing machinery is mostly known, the kinetics of splicing, the catalytic activity of splicing factors and the interdependency of transcription, splicing and mRNA 3′ end f...

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Detalhes bibliográficos
Main Authors: Aitken, Stuart, Alexander, Ross D., Beggs, Jean D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192812/
https://ncbi.nlm.nih.gov/pubmed/22022255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002215
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