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Real-time imaging of cotranscriptional splicing reveals a kinetic model that reduces noise: implications for alternative splicing regulation

Splicing is a key process that expands the coding capacity of genomes. Its kinetics remain poorly characterized, and the distribution of splicing time caused by the stochasticity of single splicing events is expected to affect regulation efficiency. We conducted a small-scale survey on 40 introns in...

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Библиографические подробности
Главные авторы: Schmidt, Ute, Basyuk, Eugenia, Robert, Marie-Cécile, Yoshida, Minoru, Villemin, Jean-Philippe, Auboeuf, Didier, Aitken, Stuart, Bertrand, Edouard
Формат: Artigo
Язык:Inglês
Опубликовано: The Rockefeller University Press 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3105549/
https://ncbi.nlm.nih.gov/pubmed/21624952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201009012
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