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Transmission Selects for HIV-1 Strains of Intermediate Virulence: A Modelling Approach

Recent data shows that HIV-1 is characterised by variation in viral virulence factors that is heritable between infections, which suggests that viral virulence can be naturally selected at the population level. A trade-off between transmissibility and duration of infection appears to favour viruses...

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Bibliographic Details
Main Authors: Shirreff, George, Pellis, Lorenzo, Laeyendecker, Oliver, Fraser, Christophe
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192807/
https://ncbi.nlm.nih.gov/pubmed/22022243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002185
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